Package: factorial2x2 0.2.0

factorial2x2: Design and Analysis of a 2x2 Factorial Trial

Used for the design and analysis of a 2x2 factorial trial for a time-to-event endpoint. It performs power calculations and significance testing as well as providing estimates of the relevant hazard ratios and the corresponding 95% confidence intervals. Important reference papers include Slud EV. (1994) <https://www.ncbi.nlm.nih.gov/pubmed/8086609> Lin DY, Gong J, Gallo P, Bunn PH, Couper D. (2016) <doi:10.1111/biom.12507> Leifer ES, Troendle JF, Kolecki A, Follmann DA. (2020) <https://github.com/EricSLeifer/factorial2x2/blob/master/Leifer%20et%20al.%20paper.pdf>.

Authors:Eric Leifer and James Troendle

# Install 'factorial2x2' in R:

install.packages('factorial2x2', repos = c('https://ericsleifer.r-universe.dev', 'https://cloud.r-project.org'))

Datasets:

On CRAN:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

Last updated 4 years agofrom:b1d6917cf0. Checks:OK: 7. Indexed: yes.

Eric Leifer and James Troendle

Last update: 2020-04-27
Started: 2019-09-07

Help page	Topics
Hazard ratios and correlations for the 2x2 statistics	cor2x2
Critical values for the Equal Allocation 3, Proportional Allocation 2, and Equal Allocation 2 procedures	crit2x2
Calculate event probabilities	eventProb
Significance testing for the Proportional Allocation 2, Equal Allocation 3, Equal Allocation 2 procedures	fac2x2analyze
Power for the Equal Allocation 3, Proportional Allocation 2, and Equal Allocation 2 procedures.	fac2x2design
Unstratified (ordinary) logrank power	lgrkPower
Power of the Equal Allocation 2 procedure	powerEA2
Power of the Equal Allocation 3 procedure	powerEA3
Power of the Proportional Allocation 2 procedure	powerPA2
Round down a negative number	roundDown
Simulated 2x2 factorial trial data	simdat
Simulated 2x2 factorial trial data	simdata
Simulated 2x2 factorial trial data	simdataSub
Stratified (overall) logrank power	strLgrkPower